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Correction of the retinal dystrophy phenotype of the RCS rat by viral gene transfer of Mertk

The Royal College of Surgeons (RCS) rat is a widely studied animal model of retinal degeneration in which the inability of the retinal pigment epithelium (RPE) to phagocytize shed photoreceptor outer segments leads to a progressive loss of rod and cone photoreceptors. We recently used positional clo...

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Detalhes bibliográficos
Main Authors: Vollrath, Douglas, Feng, Wei, Duncan, Jacque L., Yasumura, Douglas, D'Cruz, Patricia M., Chappelow, Aimee, Matthes, Michael T., Kay, Mark A., LaVail, Matthew M.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC60097/
https://ncbi.nlm.nih.gov/pubmed/11592982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.221364198
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