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Functional Properties and Molecular Architecture of Leukotriene A4 Hydrolase, a Pivotal Catalyst of Chemotactic Leukotriene Formation

The leukotrienes are a family of lipid mediators involved in inflammation and allergy. Leukotriene B(4) is a classical chemoattractant, which triggers adherence and aggregation of leukocytes to the endothelium at only nM concentrations. In addition, leukotriene B(4) modulates immune responses, parti...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:ScientificWorldJournal
Hauptverfasser: Haeggström, Jesper Z., Nordlund, Pär, Thunnissen, Marjolein M.G.M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: TheScientificWorldJOURNAL 2002
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6009643/
https://ncbi.nlm.nih.gov/pubmed/12806167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1100/tsw.2002.810
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