Widespread enhancer activation via ERα mediates estrogen response in vivo during uterine development

Little is known regarding how steroid hormone exposures impact the epigenetic landscape in a living organism. Here, we took a global approach to understanding how exposure to the estrogenic chemical, diethylstilbestrol (DES), affects the neonatal mouse uterine epigenome. Integration of RNA- and ChIP...

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Podrobná bibliografie
Vydáno v:Nucleic Acids Res
Hlavní autoři: Jefferson, Wendy N, Kinyamu, H Karimi, Wang, Tianyuan, Miranda, Adam X, Padilla-Banks, Elizabeth, Suen, Alisa A, Williams, Carmen J
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2018
Témata:
Gene regulation, Chromatin and Epigenetics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6009594/
https://ncbi.nlm.nih.gov/pubmed/29648668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky260
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