Persistently Altered Epigenetic Marks in the Mouse Uterus After Neonatal Estrogen Exposure

Neonatal exposure to diethylstilbestrol (DES) causes permanent alterations in female reproductive tract gene expression, infertility, and uterine cancer in mice. To determine whether epigenetic mechanisms could explain these phenotypes, we first tested whether DES altered uterine expression of chrom...

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Autores principales: Jefferson, Wendy N., Chevalier, Dominique M., Phelps, Jazma Y., Cantor, Amy M., Padilla-Banks, Elizabeth, Newbold, Retha R., Archer, Trevor K., Kinyamu, H. Karimi, Williams, Carmen J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Endocrine Society 2013
Materias:
Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3787132/
https://ncbi.nlm.nih.gov/pubmed/24002655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2013-1211
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