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Product-oriented chemical surface modification of a levansucrase (SacB) via an ene-type reaction

Carbohydrate processing enzymes are sophisticated tools of living systems that have evolved to execute specific reactions on sugars. Here we present for the first time the site-selective chemical modification of exposed tyrosine residues in SacB, a levansucrase from Bacillus megaterium (Bm-LS) for e...

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Détails bibliographiques
Publié dans:Chem Sci
Auteurs principaux: Ortiz-Soto, Maria Elena, Ertl, Julia, Mut, Jürgen, Adelmann, Juliane, Le, Thien Anh, Shan, Junwen, Teßmar, Jörg, Schlosser, Andreas, Engels, Bernd, Seibel, Jürgen
Format: Artigo
Langue:Inglês
Publié: Royal Society of Chemistry 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6009436/
https://ncbi.nlm.nih.gov/pubmed/30009003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8sc01244j
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