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Impaired coordination of nucleophile and increased hydrophobicity in the +1 subsite shift levansucrase activity towards transfructosylation

Bacterial levansucrases produce β(2,6)-linked levan-type polysaccharides using sucrose or sucrose analogs as donor/acceptor substrates. However, the dominant reaction of Bacillus megaterium levansucrase (Bm-LS) is hydrolysis. Single domain levansucrases from Gram-positive bacteria display a wide sub...

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Detalhes bibliográficos
Publicado no:Glycobiology
Main Authors: Ortiz-Soto, Maria Elena, Possiel, Christian, Görl, Julian, Vogel, Andreas, Schmiedel, Ramona, Seibel, Jürgen
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5881714/
https://ncbi.nlm.nih.gov/pubmed/28575294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cwx050
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