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Mass Spectral Detection of Diethoxyphospho-Tyrosine Adducts on Proteins from HEK293 Cells Using Monoclonal Antibody depY for Enrichment

[Image: see text] Chronic illness from exposure to organophosphorus toxicants is hypothesized to involve modification of unknown proteins. Tyrosine in proteins that have no active site serine readily reacts with organophosphorus toxicants. We developed a monoclonal antibody, depY, that specifically...

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Bibliografske podrobnosti
izdano v:Chem Res Toxicol
Main Authors: Onder, Seda, Schopfer, Lawrence M., Tacal, Ozden, Blake, Thomas A., Johnson, Rudolph C., Lockridge, Oksana
Format: Artigo
Jezik:Inglês
Izdano: American Chemical Society 2018
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6008731/
https://ncbi.nlm.nih.gov/pubmed/29775289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrestox.8b00083
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