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Monoclonal antibody that recognizes diethoxyphospho-tyrosine modified proteins and peptides independent of surrounding amino acids

Acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) are irreversibly inhibited by organophosphorus pesticides through formation of a covalent bond with the active site serine. Proteins that have no active site serine, for example albumin, are covalently modified on tyrosine and lysine. Chro...

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Détails bibliographiques
Publié dans:Chem Res Toxicol
Auteurs principaux: Onder, Seda, Dafferner, Alicia J., Schopfer, Lawrence M., Xiao, Gaoping, Yerramalla, Udaya, Tacal, Ozden, Blake, Thomas A., Johnson, Rudolph C., Lockridge, Oksana
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6006506/
https://ncbi.nlm.nih.gov/pubmed/29137457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrestox.7b00288
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