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Mass Spectral Detection of Diethoxyphospho-Tyrosine Adducts on Proteins from HEK293 Cells Using Monoclonal Antibody depY for Enrichment

[Image: see text] Chronic illness from exposure to organophosphorus toxicants is hypothesized to involve modification of unknown proteins. Tyrosine in proteins that have no active site serine readily reacts with organophosphorus toxicants. We developed a monoclonal antibody, depY, that specifically...

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Publicado en:Chem Res Toxicol
Autores principales: Onder, Seda, Schopfer, Lawrence M., Tacal, Ozden, Blake, Thomas A., Johnson, Rudolph C., Lockridge, Oksana
Formato: Artigo
Lenguaje:Inglês
Publicado: American Chemical Society 2018
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6008731/
https://ncbi.nlm.nih.gov/pubmed/29775289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrestox.8b00083
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