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Mass Spectral Detection of Diethoxyphospho-Tyrosine Adducts on Proteins from HEK293 Cells Using Monoclonal Antibody depY for Enrichment

[Image: see text] Chronic illness from exposure to organophosphorus toxicants is hypothesized to involve modification of unknown proteins. Tyrosine in proteins that have no active site serine readily reacts with organophosphorus toxicants. We developed a monoclonal antibody, depY, that specifically...

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Detalhes bibliográficos
Publicado no:Chem Res Toxicol
Main Authors: Onder, Seda, Schopfer, Lawrence M., Tacal, Ozden, Blake, Thomas A., Johnson, Rudolph C., Lockridge, Oksana
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2018
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6008731/
https://ncbi.nlm.nih.gov/pubmed/29775289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrestox.8b00083
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