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Neuron-specific HuR-deficient mice spontaneously develop motor neuron disease
Human antigen R (HuR), is an RNA binding protein in the human antigen protein family. To study the neuron-specific function of HuR, we generated inducible, neuron-specific HuR-deficient mice of both sexes. After tamoxifen-induced deletion of HuR, these mice developed a phenotype consisting of poor b...
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| Publicat a: | J Immunol |
|---|---|
| Autors principals: | , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6008238/ https://ncbi.nlm.nih.gov/pubmed/29760195 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1701501 |
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