Myeloid-derived suppressor cells impair B cell responses in lung cancer through IL-7 and STAT5

Myeloid-derived suppressor cells (MDSCs) are known suppressors of anti-tumor immunity, affecting amino acid metabolism and T cell function in the tumor microenvironment (TME). However, it is unknown if MDSCs regulate B cell responses during tumor progression. Using a syngeneic mouse model of lung ca...

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Pubblicato in:J Immunol
Autori principali: Wang, Yong, Schafer, Cara C., Hough, Kenneth P., Tousif, Sultan, Duncan, Steven R., Kearney, John F., Ponnazhagan, Selvarangan, Hsu, Hui-Chen, Deshane, Jessy S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6008229/
https://ncbi.nlm.nih.gov/pubmed/29752311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1701069
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