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Reduced Cooperativity of Voltage-Gated Sodium Channels in the Hippocampal Interneurons of Aged Mouse Model of Alzheimer’s Disease

Beta amyloid (Aβ) associated with Alzheimer’s disease (AD) leads to abnormal behavior in inhibitory neurons, resulting in hyperactive neuronal networks, epileptiform behavior, disrupted gamma rhythms, and aberrant synaptic plasticity. Previously, we used a dual modeling-experimental approach to expl...

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Detalhes bibliográficos
Publicado no:Eur Biophys J
Main Authors: Perez, Carlos, Ullah, Ghanim
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6008176/
https://ncbi.nlm.nih.gov/pubmed/29427204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00249-017-1274-y
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