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Reduced Cooperativity of Voltage-Gated Sodium Channels in the Hippocampal Interneurons of Aged Mouse Model of Alzheimer’s Disease

Beta amyloid (Aβ) associated with Alzheimer’s disease (AD) leads to abnormal behavior in inhibitory neurons, resulting in hyperactive neuronal networks, epileptiform behavior, disrupted gamma rhythms, and aberrant synaptic plasticity. Previously, we used a dual modeling-experimental approach to expl...

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Bibliografische gegevens
Gepubliceerd in:Eur Biophys J
Hoofdauteurs: Perez, Carlos, Ullah, Ghanim
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6008176/
https://ncbi.nlm.nih.gov/pubmed/29427204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00249-017-1274-y
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