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Reduced Cooperativity of Voltage-Gated Sodium Channels in the Hippocampal Interneurons of Aged Mouse Model of Alzheimer’s Disease
Beta amyloid (Aβ) associated with Alzheimer’s disease (AD) leads to abnormal behavior in inhibitory neurons, resulting in hyperactive neuronal networks, epileptiform behavior, disrupted gamma rhythms, and aberrant synaptic plasticity. Previously, we used a dual modeling-experimental approach to expl...
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Publicado no: | Eur Biophys J |
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Main Authors: | , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2018
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6008176/ https://ncbi.nlm.nih.gov/pubmed/29427204 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00249-017-1274-y |
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