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PLCγ1-PKCε-IP(3)R1 signaling plays an important role in hypoxia-induced calcium response in pulmonary artery smooth muscle cells
Hypoxia-induced pulmonary vasoconstriction (HPV) is attributed to an increase in intracellular Ca(2+) concentration ([Ca(2+)](i)) in pulmonary artery smooth muscle cells (PASMCs). We have reported that phospholipase C-γ1 (PLCγ1) plays a significant role in the hypoxia-induced increase in [Ca(2+)](i)...
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| Publicado no: | Am J Physiol Lung Cell Mol Physiol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6008133/ https://ncbi.nlm.nih.gov/pubmed/29388468 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00243.2017 |
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