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Selective regulation of osteoclast adhesion and spreading by PLCγ/PKCα-PKCδ/RhoA-Rac1 signaling

Bone resorption by multinucleated osteoclasts is a multistep process involving adhesion to the bone matrix, migration to resorption sites, and formation of sealing zones and ruffled borders. Macrophage colony-stimulating factor (M-CSF) and osteopontin (OPN) have been shown to be involved in the bone...

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Pubblicato in:BMB Rep
Autori principali: Kim, Jin-Man, Lee, Kyunghee, Jeong, Daewon
Natura: Artigo
Lingua:Inglês
Pubblicazione: Korean Society for Biochemistry and Molecular Biology 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5988577/
https://ncbi.nlm.nih.gov/pubmed/29301608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5483/BMBRep.2018.51.5.198
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