Organ-level right ventricular dysfunction with preserved Frank-Starling mechanism in a mouse model of pulmonary arterial hypertension

Pulmonary arterial hypertension (PAH) is a rapidly fatal disease in which mortality is due to right ventricular (RV) failure. It is unclear whether RV dysfunction initiates at the organ level or the subcellular level or both. We hypothesized that chronic pressure overload-induced RV dysfunction begi...

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Detalhes bibliográficos
Publicado no:J Appl Physiol (1985)
Main Authors: Wang, Zhijie, Patel, Jitandrakumar R., Schreier, David A., Hacker, Timothy A., Moss, Richard L., Chesler, Naomi C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6008075/
https://ncbi.nlm.nih.gov/pubmed/29369739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.00725.2017
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