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Organ-level right ventricular dysfunction with preserved Frank-Starling mechanism in a mouse model of pulmonary arterial hypertension

Pulmonary arterial hypertension (PAH) is a rapidly fatal disease in which mortality is due to right ventricular (RV) failure. It is unclear whether RV dysfunction initiates at the organ level or the subcellular level or both. We hypothesized that chronic pressure overload-induced RV dysfunction begi...

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Vydáno v:J Appl Physiol (1985)
Hlavní autoři: Wang, Zhijie, Patel, Jitandrakumar R., Schreier, David A., Hacker, Timothy A., Moss, Richard L., Chesler, Naomi C.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6008075/
https://ncbi.nlm.nih.gov/pubmed/29369739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.00725.2017
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