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Mass spectrometric measurement of urinary kynurenine-to-tryptophan ratio in children with and without urinary tract infection
BACKGROUND: Indoleamine-2,3-dioxygenase (IDO) catalyzes the first step of tryptophan (Trp) catabolism, yielding kynurenine (Kyn) metabolites. The kynurenine-to-tryptophan (K/T) ratio is used as a surrogate for biological IDO enzyme activity. IDO expression is increased during Escherichia coli urinar...
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| Publicado en: | Clin Biochem |
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| Autores principales: | , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2018
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6007864/ https://ncbi.nlm.nih.gov/pubmed/29679555 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clinbiochem.2018.04.014 |
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