The kynurenine to tryptophan ratio as a prognostic tool for glioblastoma patients enrolling in immunotherapy

We hypothesized that peripheral tryptophan (Trp) and/or kynurenine (Kyn) levels would provide prognostic value for physicians planning to enroll glioblastoma multiforme (GBM) patients in immunotherapy. GBM is the most common form of malignant glioma in adults. Despite aggressive surgical resection,...

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Detalhes bibliográficos
Publicado no:J Clin Neurosci
Main Authors: Zhai, Lijie, Dey, Mahua, Lauing, Kristen L., Gritsina, Galina, Kaur, Rajwant, Lukas, Rimas V., Nicholas, M. Kelly, Rademaker, Alfred W., Dostal, Carlos R., McCusker, Robert H., Raizer, Jeffrey J., Parsa, Andrew T., Bloch, Orin, Wainwright, Derek A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4548799/
https://ncbi.nlm.nih.gov/pubmed/26279502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jocn.2015.06.018
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