Chargement en cours...
miR-122 does not impact recognition of the HCV genome by innate sensors of RNA but rather protects the 5′ end from the cellular pyrophosphatases, DOM3Z and DUSP11
Hepatitis C virus (HCV) recruits two molecules of the liver-specific microRNA-122 (miR-122) to the 5′ end of its genome. This interaction promotes viral RNA accumulation, but the precise mechanism(s) remain incompletely understood. Previous studies suggest that miR-122 is able to protect the HCV gen...
Enregistré dans:
| Publié dans: | Nucleic Acids Res |
|---|---|
| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2018
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6007490/ https://ncbi.nlm.nih.gov/pubmed/29672716 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky273 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|