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Modulation of GB Virus B RNA Abundance by MicroRNA-122: Dependence on and Escape from MicroRNA-122 Restriction

Hepatitis C virus (HCV) RNA forms an unusual interaction with human microRNA-122 (miR-122) that promotes viral RNA accumulation in cultured human liver cells and in the livers of infected chimpanzees. GB virus B (GBV-B) is a hepatotropic virus and close relative of HCV. Thus, GBV-B has been used as...

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Autori principali: Sagan, Selena M., Sarnow, Peter, Wilson, Joyce A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3700295/
https://ncbi.nlm.nih.gov/pubmed/23616647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00378-13
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