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Masking the 5′ terminal nucleotides of the hepatitis C virus genome by an unconventional microRNA-target RNA complex

Hepatitis C virus subverts liver-specific microRNA, miR-122, to upregulate viral RNA abundance in both infected cultured cells and in the liver of infected chimpanzees. These findings have identified miR-122 as an attractive antiviral target. Thus, it is imperative to know whether a distinct functio...

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Détails bibliographiques
Auteurs principaux: Machlin, Erica S., Sarnow, Peter, Sagan, Selena M.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3044371/
https://ncbi.nlm.nih.gov/pubmed/21220300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1012464108
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