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A186 INVESTIGATION OF THE PROTECTIVE ROLE OF MIR-122 AGAINST CELLULAR SENSORS OF RNA AT THE 5’ TERMINUS OF HEPATITIS C VIRUS GENOME

BACKGROUND: Approximately 200 million individuals worldwide are infected by hepatitis C virus (HCV). MicroRNA-122 (miR-122) is a highly abundant liver-specific miRNA shown to interact at two miRNA-binding sites in the 5’ end of the HCV genome. This unusual interaction promotes HCV RNA accumulation i...

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Bibliographische Detailangaben
Veröffentlicht in:J Can Assoc Gastroenterol
Hauptverfasser: Bernier, A, Amador, Y, Sagan, S, Wilson, J A
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6507589/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jcag/gwy008.187
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