High CD44 expression mediates p62-associated NFE2L2/NRF2 activation in breast cancer stem cell-like cells: Implications for cancer stem cell resistance

Cluster of differentiation 44 (CD44) is the most common cancer stem cell (CSC) marker and high CD44 expression has been associated with anticancer drug resistance, tumor recurrence, and metastasis. In this study, we aimed to investigate the molecular mechanism by which CD44 and nuclear factor erythr...

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Bibliographic Details
Published in:Redox Biol
Main Authors: Ryoo, In-geun, Choi, Bo-hyun, Ku, Sae-Kwang, Kwak, Mi-Kyoung
Format: Artigo
Language:Inglês
Published: Elsevier 2018
Subjects:
Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6006726/
https://ncbi.nlm.nih.gov/pubmed/29729523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2018.04.015
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