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Stapling of unprotected helical peptides via photo-induced intramolecular thiol–yne hydrothiolation
Peptide stapling emerged as a versatile strategy to recapitulate the bioactive helical conformation of unstructured short peptides in water to improve their therapeutic properties in targeting intracellular “undruggable” targets. Here, we describe the development of photo-induced intramolecular thio...
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| Yayımlandı: | Chem Sci |
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| Asıl Yazarlar: | , , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Royal Society of Chemistry
2016
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6006495/ https://ncbi.nlm.nih.gov/pubmed/29997825 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6sc00106h |
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