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The correlation between crizotinib efficacy and molecular heterogeneity by next-generation sequencing in non-small cell lung cancer

BACKGROUND: Non-small cell lung cancer (NSCLC) patients with EML4-ALK fusion exhibited various durations of response to crizotinib. Molecular heterogeneity is also one of the factors associated with resistance to crizotinib. This study investigated the relevance of molecular heterogeneity to the cli...

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Dades bibliogràfiques
Publicat a:J Thorac Dis
Autors principals: Lv, Tangfeng, Zou, Qian, Song, Zhengbo, Liu, Hongbing, Wang, Qiming, Song, Yong
Format: Artigo
Idioma:Inglês
Publicat: AME Publishing Company 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6006122/
https://ncbi.nlm.nih.gov/pubmed/29997961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/jtd.2018.05.55
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