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Comparison of Next-Generation Sequencing and Ventana Immunohistochemistry in Detecting ALK Rearrangements and Predicting the Efficacy of First-Line Crizotinib in Patients with Advanced Non-Small Cell Lung Cancer

INTRODUCTION: Reliable diagnostic approaches to detect ALK rearrangement are critical for selecting patients eligible for crizotinib therapy. This study aimed to compare next-generation sequencing (NGS) and Ventana immunohistochemistry (IHC) in evaluating ALK rearrangements and evaluate their impact...

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Bibliografiske detaljer
Udgivet i:Onco Targets Ther
Main Authors: Zeng, Liang, Li, Yizhi, Xu, Qinqin, Jiang, Wenjuan, Lizaso, Analyn, Mao, Xinru, Zhang, Yongchang, Yang, Nong, Wang, Zhenxing
Format: Artigo
Sprog:Inglês
Udgivet: Dove 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7398878/
https://ncbi.nlm.nih.gov/pubmed/32801744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S265974
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