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The correlation between crizotinib efficacy and molecular heterogeneity by next-generation sequencing in non-small cell lung cancer
BACKGROUND: Non-small cell lung cancer (NSCLC) patients with EML4-ALK fusion exhibited various durations of response to crizotinib. Molecular heterogeneity is also one of the factors associated with resistance to crizotinib. This study investigated the relevance of molecular heterogeneity to the cli...
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Publicado no: | J Thorac Dis |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
AME Publishing Company
2018
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6006122/ https://ncbi.nlm.nih.gov/pubmed/29997961 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/jtd.2018.05.55 |
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