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Structure/function of the soluble guanylyl cyclase catalytic domain

Soluble guanylyl cyclase (GC-1) is the primary receptor of nitric oxide (NO) in smooth muscle cells and maintains vascular function by inducing vasorelaxation in nearby blood vessels. GC-1 converts guanosine 5′-triphosphate (GTP) into cyclic guanosine 3′,5′-monophosphate (cGMP), which acts as a seco...

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Bibliographic Details
Published in:Nitric Oxide
Main Authors: Childers, Kenneth C., Garcin, Elsa D.
Format: Artigo
Language:Inglês
Published: 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6005667/
https://ncbi.nlm.nih.gov/pubmed/29702251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.niox.2018.04.008
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