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Inhibition of Soluble Guanylyl Cyclase by Small Molecules Targeted to the Catalytic Domain
Soluble guanylyl cyclase (sGC) plays a crucial role in cyclic nucleotide signaling that regulates numerous important physiological processes. To identify new sGC inhibitors that may prevent the formation of the active catalytic domain conformation, we carried out an in silico docking screen targetin...
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| 出版年: | FEBS Lett |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5077689/ https://ncbi.nlm.nih.gov/pubmed/27654641 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.12427 |
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