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Inhibition of Soluble Guanylyl Cyclase by Small Molecules Targeted to the Catalytic Domain
Soluble guanylyl cyclase (sGC) plays a crucial role in cyclic nucleotide signaling that regulates numerous important physiological processes. To identify new sGC inhibitors that may prevent the formation of the active catalytic domain conformation, we carried out an in silico docking screen targetin...
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| Udgivet i: | FEBS Lett |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5077689/ https://ncbi.nlm.nih.gov/pubmed/27654641 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.12427 |
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