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Transforming Benzylic Amines into Diarylmethanes: Cross-Couplings of Benzylic Pyridinium Salts via C–N Bond Activation

A nickel-catalyzed cross-coupling of benzylic pyridinium salts with arylboronic acids was developed. Coupled with chemoselective pyridinium formation, this method allows benzyl primary amines to be efficiently converted to di(hetero)arylmethanes. Excellent heteroaryl and functional group tolerance i...

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Bibliografiset tiedot
Julkaisussa:Org Lett
Päätekijät: Liao, Jennie, Guan, Weiye, Boscoe, Brian P., Tucker, Joseph W., Tomlin, John W., Garnsey, Michelle, Watson, Mary P.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6005208/
https://ncbi.nlm.nih.gov/pubmed/29745674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.8b01062
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