Change of Amyloid-β 1-42 Toxic Conformer Ratio After Cerebrospinal Fluid Diversion Predicts Long-Term Cognitive Outcome in Patients with Idiopathic Normal Pressure Hydrocephalus

BACKGROUND: Alzheimer’s disease (AD) pathology in idiopathic normal pressure hydrocephalus (iNPH) contributes to poor shunt responses. Amyloid-β 1– 42 (Aβ(42)) toxic conformer was recently identified with features of rapid oligomerization, strong neurotoxicity and synaptotoxicity. OBJECTIVE: This ob...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:J Alzheimers Dis
Glavni autori: Akiba, Chihiro, Nakajima, Madoka, Miyajima, Masakazu, Ogino, Ikuko, Motoi, Yumiko, Kawamura, Kaito, Adachi, Satoshi, Kondo, Akihide, Sugano, Hidenori, Tokuda, Takahiko, Irie, Kazuhiro, Arai, Hajime
Format: Artigo
Jezik:Inglês
Izdano: IOS Press 2018
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6004932/
https://ncbi.nlm.nih.gov/pubmed/29710721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-180059
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items