Gravin regulates centrosome function through PLK1

We propose to understand how the mitotic kinase PLK1 drives chromosome segregation errors, with a specific focus on Gravin, a PLK1 scaffold. In both three-dimensional primary prostate cancer cell cultures that are prone to Gravin depletion and Gravin short hairpin RNA (shRNA)–treated cells, an incre...

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Bibliografiska uppgifter
I publikationen:Mol Biol Cell
Huvudupphovsmän: Colicino, Erica G., Garrastegui, Alice M., Freshour, Judy, Santra, Peu, Post, Dawn E., Kotula, Leszek, Hehnly, Heidi
Materialtyp: Artigo
Språk:Inglês
Publicerad: The American Society for Cell Biology 2018
Ämnen:
Brief Reports
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6004580/
https://ncbi.nlm.nih.gov/pubmed/29282278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E17-08-0524
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