Liver kinase B1 regulates the centrosome via PLK1

Liver kinase B1 (LKB1) is a tumor suppressor mutationally inactivated in Peutz–Jeghers syndrome (PJS) and various sporadic cancers. Although LKB1 encodes a kinase that possesses multiple functions, no individual hypothesis posed to date has convincingly explained how loss of LKB1 contributes to carc...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Death Dis
Egile Nagusiak: Werle, K, Chen, J, Xu, H-G, Zhao, R-X, He, Q, Lu, C, Cui, R, Liang, J, Li, Y-L, Xu, Z-X
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2014
Gaiak:
Original Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5424112/
https://ncbi.nlm.nih.gov/pubmed/24722282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.135
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