Increase in chemokine CXCL1 by ERβ ligand treatment is a key mediator in promoting axon myelination

Estrogen receptor β (ERβ) ligands promote remyelination in mouse models of multiple sclerosis. Recent work using experimental autoimmune encephalomyelitis (EAE) has shown that ERβ ligands induce axon remyelination, but impact peripheral inflammation to varying degrees. To identify if ERβ ligands ini...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Karim, Hawra, Kim, Sung Hoon, Lapato, Andrew S., Yasui, Norio, Katzenellenbogen, John A., Tiwari-Woodruff, Seema K.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2018
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6004485/
https://ncbi.nlm.nih.gov/pubmed/29844175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1721732115
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