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Selection of Plasmodium falciparum cytochrome B mutants by putative PfNDH2 inhibitors
Malaria control is threatened by a limited pipeline of effective pharmaceuticals against drug-resistant strains of Plasmodium falciparum. Components of the mitochondrial electron transport chain (ETC) are attractive targets for drug development, owing to exploitable differences between the parasite...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6004454/ https://ncbi.nlm.nih.gov/pubmed/29844160 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1804492115 |
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