The mTOR-S6 kinase pathway promotes stress granule assembly

Stress granules are cytoplasmic mRNA-protein complexes that form upon the inhibition of translation initiation and promote cell survival in response to environmental insults. However, they are often associated with pathologies, including neurodegeneration and cancer, and changes in their dynamics ar...

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Publicat a:Cell Death Differ
Autors principals: Sfakianos, Aristeidis P., Mellor, Laura E., Pang, Yoke Fei, Kritsiligkou, Paraskevi, Needs, Hope, Abou-Hamdan, Hussein, Désaubry, Laurent, Poulin, Gino B., Ashe, Mark P., Whitmarsh, Alan J.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6004310/
https://ncbi.nlm.nih.gov/pubmed/29523872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-018-0076-9
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