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Functional precision medicine identifies novel druggable targets and therapeutic options in head and neck cancer

PURPOSE: Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer worldwide with high mortality and a lack of targeted therapies. To identify and prioritize druggable targets, we performed genome analysis together with genome-scale siRNA and oncology drug profiling using low pas...

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書目詳細資料
發表在:Clin Cancer Res
Main Authors: Xu, Chang, Nikolova, Olga, Basom, Ryan S., Mitchell, Ryan M., Shaw, Reid, Moser, Russell D., Park, Heuijoon, Gurley, Kay E., Kao, Michael C., Green, Carlos L., Schaub, Franz X., Diaz, Robert L., Swan, Hallie A., Jang, In S., Guinney, Justin, Gadi, Vijayakrishna K., Margolin, Adam A., Grandori, Carla, Kemp, Christopher J., Méndez, Eduardo
格式: Artigo
語言:Inglês
出版: 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6004257/
https://ncbi.nlm.nih.gov/pubmed/29599409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-17-1339
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