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Analysis of novel endosome-to-Golgi retrieval genes reveals a role for PLD3 in regulating endosomal protein sorting and amyloid precursor protein processing

The processing of amyloid precursor protein (APP) to the neurotoxic pro-aggregatory Aβ peptide is controlled by the mechanisms that govern the trafficking and localisation of APP. We hypothesised that genes involved in endosomal protein sorting could play an important role in regulating APP processi...

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Bibliografiska uppgifter
I publikationen:Cell Mol Life Sci
Huvudupphovsmän: Mukadam, Aamir S., Breusegem, Sophia Y., Seaman, Matthew N. J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Springer International Publishing 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6003983/
https://ncbi.nlm.nih.gov/pubmed/29368044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-018-2752-9
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