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Activity-dependent aberrations in gene expression and alternative splicing in a mouse model of Rett syndrome

Rett syndrome (RTT) is a severe neurodevelopmental disorder that affects about 1 in 10,000 female live births. The underlying cause of RTT is mutations in the X-linked gene, methyl-CpG-binding protein 2 (MECP2); however, the molecular mechanism by which these mutations mediate the RTT neuropathology...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Osenberg, Sivan, Karten, Ariel, Sun, Jialin, Li, Jin, Charkowick, Shaun, Felice, Christy A., Kritzer, Mary, Nguyen, Minh Vu Chuong, Yu, Peng, Ballas, Nurit
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6003366/
https://ncbi.nlm.nih.gov/pubmed/29769330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1722546115
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