Misregulation of Alternative Splicing in a Mouse Model of Rett Syndrome

Mutations in the human MECP2 gene cause Rett syndrome (RTT), a severe neurodevelopmental disorder that predominantly affects girls. Despite decades of work, the molecular function of MeCP2 is not fully understood. Here we report a systematic identification of MeCP2-interacting proteins in the mouse...

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Foilsithe in:PLoS Genet
Main Authors: Li, Ronghui, Dong, Qiping, Yuan, Xinni, Zeng, Xin, Gao, Yu, Chiao, Cassandra, Li, Hongda, Zhao, Xinyu, Keles, Sunduz, Wang, Zefeng, Chang, Qiang
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2016
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4924826/
https://ncbi.nlm.nih.gov/pubmed/27352031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006129
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