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Structural basis of O-GlcNAc recognition by mammalian 14-3-3 proteins

O-GlcNAc is an intracellular posttranslational modification that governs myriad cell biological processes and is dysregulated in human diseases. Despite this broad pathophysiological significance, the biochemical effects of most O-GlcNAcylation events remain uncharacterized. One prevalent hypothesis...

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Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Toleman, Clifford A., Schumacher, Maria A., Yu, Seok-Ho, Zeng, Wenjie, Cox, Nathan J., Smith, Timothy J., Soderblom, Erik J., Wands, Amberlyn M., Kohler, Jennifer J., Boyce, Michael
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6003352/
https://ncbi.nlm.nih.gov/pubmed/29784830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1722437115
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