Quantitative phosphoproteomic analysis reveals reciprocal activation of receptor tyrosine kinases between cancer epithelial cells and stromal fibroblasts

BACKGROUND: Cancer-associated fibroblasts (CAFs) are one of the most important components of tumor stroma and play a key role in modulating tumor growth. However, a mechanistic understanding of how CAFs communicate with tumor cells to promote their proliferation and invasion is far from complete. A...

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Détails bibliographiques
Publié dans:Clin Proteomics
Auteurs principaux: Wu, Xinyan, Zahari, Muhammad Saddiq, Renuse, Santosh, Sahasrabuddhe, Nandini A., Chaerkady, Raghothama, Kim, Min-Sik, Fackler, Mary Jo, Stampfer, Martha, Gabrielson, Edward, Sukumar, Saraswati, Pandey, Akhilesh
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2018
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6003199/
https://ncbi.nlm.nih.gov/pubmed/29946230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12014-018-9197-x
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