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Antimicrobial sulfonamides clear latent Kaposi Sarcoma Herpesvirus infection and impair MDM2-p53 complex formation
Kaposi Sarcoma Herpesvirus (KSHV), also known as Human Herpesvirus 8, is the causative agent of Kaposi sarcoma; this malignant angiosarcoma is usually treated with conventional anti-tumor agents, which can control disease evolution, but do not clear the latent KSHV episome that binds to cellular DNA...
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| Pubblicato in: | J Antibiot (Tokyo) |
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| Autori principali: | , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6002838/ https://ncbi.nlm.nih.gov/pubmed/28611469 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ja.2017.67 |
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