Deciphering the late steps of rifamycin biosynthesis

Rifamycin-derived drugs, including rifampin, rifabutin, rifapentine, and rifaximin, have long been used as first-line therapies for the treatment of tuberculosis and other deadly infections. However, the late steps leading to the biosynthesis of the industrially important rifamycin SV and B remain l...

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Publicat a:Nat Commun
Autors principals: Qi, Feifei, Lei, Chao, Li, Fengwei, Zhang, Xingwang, Wang, Jin, Zhang, Wei, Fan, Zhen, Li, Weichao, Tang, Gong-Li, Xiao, Youli, Zhao, Guoping, Li, Shengying
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6002545/
https://ncbi.nlm.nih.gov/pubmed/29904078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04772-x
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