Chimeric HCMV/HSV-1 and Δγ(1)34.5 oncolytic herpes simplex virus elicit immune mediated antigliomal effect and antitumor memory()()

Malignant gliomas are the most common primary brain tumor and are characterized by rapid and highly invasive growth. Because of their poor prognosis, new therapeutic strategies are needed. Oncolytic virotherapy (OV) is a promising strategy for treating cancer that incorporates both direct viral repl...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Transl Oncol
Hauptverfasser: Ghonime, Mohammed G., Jackson, Josh, Shah, Amish, Roth, Justin, Li, Mao, Saunders, Ute, Coleman, Jennifer, Gillespie, G. Yancey, Markert, James M., Cassady, Kevin A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Neoplasia Press 2017
Schlagworte:
Original article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6002352/
https://ncbi.nlm.nih.gov/pubmed/29216507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2017.10.005
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