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Acute stimulation generates Tim‐3‐expressing T helper type 1 CD4 T cells that persist in vivo and show enhanced effector function

T‐cell immunoglobulin and mucin domain 3 (Tim‐3) is a surface receptor expressed by T helper type 1 (Th1) effector CD4 T cells, which are critical for defence against intracellular pathogens and have been implicated in autoimmune disease. Previous studies showed that Tim‐3 expression makes Th1 cells...

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Bibliografski detalji
Izdano u:Immunology
Glavni autori: Gorman, Jacob V., Colgan, John D.
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6002241/
https://ncbi.nlm.nih.gov/pubmed/29315553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12890
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