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Tim-3 directly enhances CD8 T cell responses to acute Listeria monocytogenes infection
Tim-3 is a surface molecule expressed throughout the immune system that can mediate both stimulatory and inhibitory effects. Previous studies have provided evidence that Tim-3 functions to enforce CD8 T cell exhaustion, a dysfunctional state associated with chronic stimulation. In contrast, the role...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3965639/ https://ncbi.nlm.nih.gov/pubmed/24567532 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1302290 |
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