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Tim-3 directly enhances CD8 T cell responses to acute Listeria monocytogenes infection

Tim-3 is a surface molecule expressed throughout the immune system that can mediate both stimulatory and inhibitory effects. Previous studies have provided evidence that Tim-3 functions to enforce CD8 T cell exhaustion, a dysfunctional state associated with chronic stimulation. In contrast, the role...

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Bibliografski detalji
Glavni autori: Gorman, Jacob V., Starbeck-Miller, Gabriel, Pham, Nhat-Long L., Traver, Geri L., Rothman, Paul B., Harty, John T., Colgan, John D.
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3965639/
https://ncbi.nlm.nih.gov/pubmed/24567532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1302290
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