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OX40 controls effector CD4(+) T-cell expansion, not follicular T helper cell generation in acute Listeria infection

To investigate the importance of OX40 signals for physiological CD4(+) T-cell responses, an endogenous antigen-specific population of CD4(+) T cells that recognise the 2W1S peptide was assessed and temporal control of OX40 signals was achieved using blocking or agonistic antibodies (Abs) in vivo. Fo...

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Detalhes bibliográficos
Publicado no:Eur J Immunol
Main Authors: Marriott, Clare L, Mackley, Emma C, Ferreira, Cristina, Veldhoen, Marc, Yagita, Hideo, Withers, David R
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4285916/
https://ncbi.nlm.nih.gov/pubmed/24771127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201344211
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